... in much larger doses, but on those constitutions with which it has any effect at all a table-spoonful is usually efficacious about ten minutes after its exhibition in the form of fluid extract. Lupulin, valerian, valerianate of zinc, and hyoscyamus (or with a much less tendency to derange the stomach, hyoscyamin in 1/10 grain doses) all have their value in the less violent cases or toward the close of the struggle. Capsicum, in the five grain doses earlier mentioned, may often be relied on ... — The Opium Habit • Horace B. Day